1.He S, Guo Z, Zhou M, et al. Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing[J]. Cell Stem Cell, 2023, 30(11): 1549-1558. e5.
哺乳动物怀孕后,母体的代谢需求、激素水平、血容量等多发面都发生了巨大变化,其中一个非常有意思的现象是,怀孕后母体的肝脏体积和重量会增大至约原来的两倍大小。然而,有关这一过程的细胞起源和调控机制尚不清楚。
2023年10月3日,西湖大学生命科学学院何灵娟团队在Cell Stem Cell发表题为“Spatial-Temporal Proliferation of Hepatocytes during Pregnancy Revealed by Genetic Lineage Tracing”的研究论文,该研究利用多种独特的遗传学工具,揭示了怀孕后母体肝脏增大的细胞起源及其调控机制。
![](/__local/5/2D/AB/AF3B518ABC51C1FED04DFBB7983_DB548EE8_E3A6.png)
原文链接:https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(23)00323-5
2.Xiao Y, Zou K, Yang J, et al. Deciphering histone H4 lysine acetylation and methylation via sortase-mediated semisynthesis[J]. Cell Reports Physical Science, 2023, 4(11).
原文链接:Deciphering histone H4 lysine acetylation and methylation via sortase-mediated semisynthesis: Cell Reports Physical Science
3.Zang Y, Liu S, Rao Z, et al. Retinoid X receptor gamma dictates the activation threshold of group 2 innate lymphoid cells and limits type 2 inflammation in the small intestine[J]. Immunity, 2023, 56(11): 2542-2554. e7.
原文链接:Retinoid X receptor gamma dictates the activation threshold of group 2 innate lymphoid cells and limits type 2 inflammation in the small intestine: Immunity