实验室：质谱与代谢平台
职位：技术员
工作职责
1、负责小分子化合物色谱-质谱方法开发和定量工作
2、负责平台高效液相色谱-三重四级杆质谱仪Sciex 6500+的运行和维护。
3、负责蛋白质组学样本前处理及蛋白质鉴定、翻译后修饰等蛋白组学定性、定量分析工作
4、负责平台Thermo Orbitrap Exlporis 480质谱仪的运行和维护。
联系方式
西湖大学（云谷校区）学术环E8-B102
chenjia@westlake.edu.cn
教育背景
2016.09-2019.06 武汉大学 药物分析学 硕士
2012.09-2016.06 湖南师范大学 制药工程 学士
工作经历
2021.11至今 西湖大学生物医学实验技术中心质谱与代谢平台 技术员
2021.10-2021.11 浙江大学农生环测试中心 技术员
2019.08-2021.09 温州医科大学科研实验中心 实验员
发表文章
1. Jia Chen, Xiao Li, Anqi Huang , Wenwen Deng , Yuxiu Xiao, Nonionic surfactants based hydrophobic deep eutectic solvents for liquid-liquid microextraction of Sudan dyes in tomato chili sauces, Food Chemistry,364 (2021) 130373
2. Jia Chen, Wenwen Deng, Xiao Li, Xuanxuan Wang, Yuxiu Xiao∗, Hexafluoroisopropanol/Brij-35 based supramolecular solvent for liquid-phase microextraction of parabens in different matrix samples, Journal of Chromatography A, 2019, 1591: 33- 43
3. Yu Zong1, Jia Chen1, Jinxuan Hou, Wenwen Deng, Xiaoyan Liao, Yuxiu Xiao, Hexafluoroisopropanol-alkyl carboxylic acid high-density supramolecular solvent based dispersive liquid-liquid microextraction of steroid sex hormones in human urine, Journal of Chromatography A, 2018, 1580: 12- 21
4. Xiao Li, Jia Chen, Caixia Yan, Xuanwei Li, Yaokun Xia, Qingwei Zhao. Alkanediol–hexafluoroisopropanol amphiphilic supramolecular solvent: Fabrication, characterization, and application potential for doping control of hormones and metabolic modulators in human urine, Microchemical Journal 201(2024)110533
5. Xiao Li , Jia Chen , Heng Wang , Xuanxuan Wang , Yuxiu Xiao, Hexafluoroisopropanol-alkanol based high-density supramolecular solvents: Fabrication, characterization and application potential as restricted access extractants，Analytica Chimica Acta 1124 (2020) 20-31
6. Xiao Li, Anqi Huang, Xiaoyan Liao, Jia Chen, Yuxiu Xiao, Restricted access supramolecular solvent based magnetic solvent bar liquid-phase microextraction for determination of non-steroidal anti-inflammatory drugs in human serum coupled with high performance liquid chromatography-tandem mass spectrometry, Journal of Chromatography A 1634 (2020) 461700
7. Wenwen Deng, Long Yu , Xiao Li, Jia Chen, Xuanxuan Wang , Zixin Deng, Yuxiu Xiao, Hexafluoroisopropanol-based hydrophobic deep eutectic solvents for dispersive liquid-liquid microextraction of pyrethroids in tea beverages and fruit juices, Food Chemistry, 2019, 274: 891- 899
8. Jia Xu, Xiao Li, Cao Li, Jia Chen, Yuxiu Xiao, Hexafluoroisopropanol-induced salt-free catanionic surfactant coacervate extraction method for determination of fluoroquinolones in milk samples, Food Chemistry, 2018, 242: 122-130
9. Anlan Yang, Shengjie Liu, Yuqi Zhang, Jia Chen, Yujing Fan, Fengxiang Wang, Yilong Zou, Shan Feng, Jianping Wu & Qi Hu, Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation. nature structural & molecular biology, 2024, https://doi.org/10.1038/s41594-023-01183-5
