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Title: Application Training for Analytical Ultracentrifugation (AUC) – A Good Helper in Structural Analysis and Protein Research

Date: September 11, 2025

AUC Hands-on Training Venue:

Room 224, Building 1, Yunqi Campus, Westlake University (Morning)

AUC Theory Exchange Venue:

Room 215, Building 1, Yunqi Campus, Westlake University (Afternoon)

Introduction:

Analytical Ultracentrifugation (AUC) is a Nobel Prize-winning technique based purely on physical principles. Under near-physiological conditions, AUC enables the study of proteins and other macromolecules in solution, providing information on sedimentation behavior, molecular weight, particle size, shape, purity, oligomerization state, and intermolecular interactions (protein–protein, protein–nucleic acid, protein–small molecule, etc.).It is widely applied to analyze the assembly and structural domains of protein complexes, aggregation behavior, conformational changes, and folding/unfolding mechanisms. With the rapid development of cryo-EM and related structural biology methods, AUC has become an increasingly important tool in understanding the structure and function of proteins.This training and exchange workshop will include hands-on practice with AUC instruments, theoretical introduction, data analysis, and practical considerations.

Agenda:

09:30–10:30 Video demonstration of sample cell assembly

10:30–12:00 Sample cell assembly and loading practice

13:30–15:00 Theoretical exchange on AUC techniques

15:00–16:00 Introduction to data analysis

16:00–17:00 Run conclusion and post-run data analysis

The hands-on training will be limited to ~15 participants.

Scan the QR Code below to register. Welcome to join us!